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Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek
the advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a
medical condition.
Heart Attack
(Acute Myocardial Infarction [AMI]; Myocardial Infarction [MI]; ST-Segment-Elevation MI [STEMI]; Transmural Myocardial infarction)
by
Rosalyn Carson-DeWitt, MD
Definition
A heart attack occurs when blood flow to the heart muscle is interrupted. Oxygen can't get to the heart muscle, causing tissue damage or tissue death.
Causes
A heart attack may be caused by:
- Accumulation of fatty plaques in the coronary arteries
- Development of a blood clot in the coronary arteries
- Embolism that affects the coronary arteries
- Narrowing of the coronary arteries
- Spasm of the coronary arteries
- Thickening of the walls of the arteries feeding the heart muscle (coronary arteries)
Risk Factors
These factors increase your chance of developing heart attack. Tell your doctor if you have any of these:
Symptoms
Symptoms include:
-
Squeezing, heavy chest pain, especially with:
- A large meal
- Cold weather
- Emotional stress
- Exercise or exertion
- Anxiety
, especially feeling a sense of doom or panic without apparent reason
- Loss of consciousness
- Nausea
- Pain in the left shoulder, left arm, or jaw
- Shortness of breath
- Sweating, clammy skin
- Weakness
Unusual symptoms of heart attack (may occur more frequently in women):
- Back and shoulder pain
- Confusion
- Fainting
- Stomach pain
Diagnosis
If you think you are having a heart attack, call 911 right away.
Tests may include:
-
Electron-beam computed tomography (EBCT)
—a type of x-ray that uses a computer to make detailed pictures of the heart, coronary arteries, and surrounding structures; may be helpful if you are at immediate risk of
coronary artery disease
- Blood tests—to look for certain enzymes found in the blood within hours or days after a heart attack
- Coronary angiography
—uses dye and x-rays to look for narrowing or blockage in the coronary arteries
- Echocardiogram
—uses high-frequency sound waves (ultrasound) to examine the size, shape, function, and motion of the heart
- Electrocardiogram (EKG)
—records the heart's activity by measuring electrical currents through the heart muscle, changes can show if there is blockage or damage
- Nuclear scanning—uses radioactive material to show areas of the heart muscle where there is diminished blood flow
- Stress test
—records the heart's electrical activity under increased physical stress, usually done days or weeks after the heart attack
- Urine tests—to look for certain substances found in the urine within hours or days after a heart attack
Treatment
Treatment includes:
-
Clot-dissolving agents (thrombolytics)—Within the first six hours after a heart attack, you may be given medications to break up blood clots in the coronary arteries.
- Other medicines that may be given include those that block the function of platelets (called platelet IIb/IIIa receptor blockers).
- Anti-anxiety medications
- Aspirin
and other antiplatelet agents
- Beta-blocking
and/or ACE inhibitor medications (frequently given)
- Cholesterol-lowering medications
(eg, statin drugs)
- Nitrate medications
- Oxygen
- Pain-relief medications (such as morphine)
Surgery
If you have severe blockages, you may need surgery. Surgery includes:
According to a review, patients who received CABG had more
angina
relief and less need for another, similar procedure. This is compared to those who received percutaneous coronary intervention (PCI). PCI involves techniques using
balloon angioplasty
or
coronary stenting
.
Physical or Rehabilitative Therapy
During
recovery
, you may need physical or rehabilitative therapy to help you regain your strength.
Treatment for Depression
You may feel
depressed
after having a heart attack.
Therapy
and
medication
can help relieve
depression
.
If you have a heart attack, follow your doctor's
instructions
.
Prevention
Preventing or treating coronary artery disease may help prevent a heart attack.
-
Ask your doctor about taking a small, daily dose of
aspirin.
- Although most people are able to tolerate such a low dose of aspirin, even this small amount can rarely lead to serious bleeding, particularly from the gastrointestinal (GI) tract .
- Aspirin may not work as well when combined with other pain medications.
-
Begin a safe
exercise program
. Follow your doctor's advice.
-
Eat a
healthful diet
. Your diet should be low in saturated fat and rich in whole grains, fruits, and vegetables.
-
If you smoke,
quit
.
-
Maintain a
healthy weight
.
-
Treat
high blood pressure
,
diabetes and high cholesterol
.
- Manage stress
.
Last reviewed: September 2011
by Michael J. Fucci, DO.
References:
-
Burke AP. Pathophysiology of acute myocardial infarction.
Med Clin North Am.
2007;91(4):553-572.
-
Heart attack. Mayo Clinic website. Available at:
http://www.mayoclinic.com/health/heart-attack/DS00094/DSECTION=8
.
Updated 2007. Accessed June 29, 2008.
-
Meier MA, Al-Badr WH, Cooper JV, et al. The new definition of myocardial infarction: diagnostic and prognostic implications in patients with acute coronary syndromes.
Arch Intern Med
. 2002;162:1585-1589.
-
Mollet NR, Cademartiri F, van Mieghem CA, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography.
Circulation
. 2005;112:2318-2323. Epub 2005 Oct 3.
-
Rakel RE, Bope ET.
Conn's Current Therapy 2001
. 53rd ed. Philadelphia, PA: WB Saunders Company; 2001.
-
What is a heart attack? American Heart Association website. Available at:
http://www.americanheart.org/presenter.jhtml?identifier=3007482
. Accessed June 29, 2008.
-
Women Physicians Congress. What you need to know about heart disease.
American Medical Association website. Available at:
http://www.ama-assn.org/ama/pub/category/11021.html
. Updated 2008. Accessed June 29, 2008.
-
11/7/2007 DynaMed's Systematic Literature Surveillance
DynaMed's Systematic Literature Surveillance
: Bravata DM, Gienger AL, McDonald KM, et al. Systematic Review: The comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery.
Ann Intern Med.
2007 Nov 20. [Epub ahead of print]
-
7/6/2009 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed/what.php
: Antithrombotic Trialists' (ATT) Collaboration, Baigent C, Blackwell L, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials.
Lancet.
2009;373:1849-1860.
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