Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.


Alopecia

(Hair Loss)
Definition

Alopecia refers to hair loss in areas of skin that normally have hair. There are two forms of alopecia: scarring and non-scarring.

Scarring is the loss of hair follicles. This form causes permanent hair loss. The most prevalent forms of scarring alopecia are:

  • Central centrifugal cicatricial alopecia
  • Cutaneous lupus erythematous
  • Fungal kerions

In the case of non-scarring, the hair shaft is gone, but the follicles are still present. It often is reversible. It can also develop into the scarring type. Non-scarring types include:

  • Alopecia areata is an autoimmune process; the cause is not known
  • Androgenetic (hereditary) alopecia
  • Telogen effluvium

Causes

Many things can cause alopecia, including:

  • Genes
    • Congenital disorders—can include problems with the hair shaft
    • Male and female-pattern baldness—usually inherited
  • Hair pulled too tightly by:
    • Cornrows
    • Hair rollers
    • Pigtails
  • Hormonal problems
  • Infections
  • Medications
    • Drugs for gout
    • Antidepressants
    • Birth control pills
    • Blood pressure and heart medications
    • Blood thinners
    • Chemotherapy for cancer treatment
    • Vitamin A
  • Stress that prompts growing hairs to rest and shed
    • Childbirth
    • Crash dieting
    • Emotional/psychological stress
    • Illness or surgery
    • Prolonged fever
    • Vitamin and nutrient deficiencies
  • Allergic reaction to medications
  • Anemia
  • Autoimmune disorders
  • Hot comb and oil treatments (can inflame the hair follicle and cause scarring)
  • Radiation therapy
  • Systemic and discoid lupus erythematosus
  • Twisting and pulling hair out due to psychiatric problems
Risk Factors

Factors that increase your chance of alopecia include:

  • Advancing age (for male and female-pattern baldness only)
  • Family history of baldness or hair loss
  • Poor nutrition
  • Pregnancy
  • Stress
Symptoms

Alopecia symptoms depend on the type of hair loss. Some of the more common symptoms include:

Male-pattern baldness:

  • Affects men and women
  • Hair falls out at the top of the head
  • Hair recedes

Female-pattern baldness:

  • Hair comes out when brushing
  • Hair thins over the entire head

Alopecia areata:

  • Fingernails and toenails with pits
  • Rapid hair loss
  • Round or oval patches of hair loss
  • Sometimes tiny hairs are visible in the patches

Stress-related:

  • Gradual shedding
  • Hairs come out with gentle pulling

Fungal infections:

  • Black dots in the patches
  • Inflammation (such as redness)
  • Itching
  • Patches of hair loss
  • Scaling
Diagnosis

The doctor will ask about your symptoms and medical history. A physical exam will be done. The doctor will examine the area(s) of hair loss, noting the pattern of hair loss and condition of the scalp.

This physical exam may include:

  • Analyzing samples of hair
  • Checking for hair loss on other parts of the body
  • Gentle pulling on the hair
  • Taking samples of scalp areas with inflammation to examine under a microscope

The doctor will ask questions about:

  • Diet
  • Hair care
  • Medication use
  • Pregnancies, menopause, and monthly menstrual cycles
  • Your personal and family medical history

Other tests may include:

  • Biopsy of the scalp—removal of a small tissue sample to be analyzed under the microscope
  • Blood tests—to help identify underlying conditions that may be causing the hair loss
Treatment

Treatment will depend on the cause of the condition. Treatments include:

Medications

To treat related conditions:

  • Antifungal shampoos and pills—to treat fungal infections
  • Changing medication that may be causing the hair loss
  • Drugs to correct a hormonal imbalance or deficiency

Direct treatment for baldness:

  • For men—a prescription drug ( finasteride )
    • Note: Pregnant women should not even handle this medication. Even a small amount absorbed through the skin of the hands can cause birth defects in baby boys.
  • Over-the-counter medication ( minoxidil )—applied to the scalp daily (must be used on a regular basis)
    • Note : If you have heart problems, discuss this drug with the doctor before using it.
  • Steroid injection into your scalp—to help speed-up hair re-growth in alopecia areata
Alternative Treatments
  • Phototherapy —potential treatment for patients with alopecia areata; usually done over 4-6 months
  • Topical immunotherapy—apply an allergen to scalp that causes local reaction like redness, itching and also induces hair growth; done if other efforts do not work
Lifestyle Changes

Be gentle with your hair. Avoid pulling it tightly. If pulled over a long period of time, scarring can occur resulting in permanent hair loss.

If treatment does not correct the hair loss, you may opt for a wig, hairpiece, or hair weaving.

If emotional stress is the cause, learn and practice stress-management techniques.

Surgery

This can involve:

  • Hair transplant—taking hair from the back and sides of the head and transplanting it in bald areas. As many as 300 grafts may be needed. You must return multiple times for the grafts.
  • Scalp reduction with flaps—cutting the scalp and pulling the areas with hair closer together.
Chemotherapy Induced
  • Currently, there are no medications available that were shown to reduce the risk of alopecia associated with cancer treatments.
  • It could be minimal, moderate or severe.
  • It is transient and completely reversible after chemotherapy is done.
Prevention

There are no prevention guidelines for the most common type of hair loss, male-pattern baldness. However, the following tips may help you avoid other types of hair loss:

  • Do not pull your hair tightly into a ponytail, cornrows, or curlers.
  • Eat healthy, well-balanced meals.
  • Learn and practice stress-management techniques.
  • Obtain medical care for acute illnesses and to manage chronic conditions.

Last reviewed: September 2011 by Ross Zeltser, MD, FAAD.

RESOURCES:
CANADIAN RESOURCES:
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